https://jmssrms.in/index.php/journal/issue/feed 2025-09-10T14:20:16+0530 Pradeep Tiwari pradeep@mripub.com Open Journal Systems <p>The SRMS Journal of Medical Sciences (SRMSJMS) is a biomedical journal with national circulation. It publishes original communications of biomedical research that advances or illuminates medical science or that educates the journal readers. It is issued six-monthly, in two volumes per year.&nbsp;Manuscripts dealing with clinical aspects will be considered for publication, provided they contain results of original investigations. Articles need to be of general interest - e.g., they cross the boundaries of specialities or are of sufficient novelty and importance that the journal's readers, whatever their speciality, should be made aware of the findings. Research papers reporting original research, review articles, and correspondence on published articles will also be considered. Papers of routine nature which are merely records of interesting cases as also those dealing with modifications of routine methodology will not be encouraged.</p> <p>&nbsp;</p> https://jmssrms.in/index.php/journal/article/view/291 2025-09-10T14:20:16+0530 Sachin Chadgal schinendo2@gmail.com

<p>Recurrent periapical pathology after root canal therapy poses<br>a clinical dilemma as both nonsurgical endodontic retreatment<br>and surgery are required. The present paper is a critical review<br>of evidence on the topic of endodontic retreatment versus apical<br>surgery in regards to indications, success rates, long-term<br>prognosis, patient-centered outcomes, and cost-effectiveness.<br>Published systematic reviews and meta-analyses to 2020<br>indicate that nonsurgical retreatment has positive long-term<br>results, especially when failure occurs due to poor obturation,<br>missed canals, or coronal leakage. On the other hand, apical<br>surgery particularly in cases where surgery is done with<br>modernized microsurgical instruments and bioceramic rootend<br>filling substances is more successful in the short-term<br>with increased likelihood of success but eventually resulting<br>in failure. Tooth- and patient-specific, restorative prognosis,<br>clinician knowledge, and modern diagnostic technologies,<br>e.g., cone-beam computed tomography, should be combined<br>in decision-making. There is evidence that there is no such<br>thing as the best modality; therefore, specific, evidence-based<br>planning of treatment is necessary to maximize clinical and<br>patient-reported outcomes. The treatment paradigm can be<br>further improved with future developments in regenerative<br>endodontics, artificial intelligence, and minimally invasive<br>treatment.</p>

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