Estimation of serum bile acid level for diagnosis of intrahepatic cholestasis of pregnancy, and its correlation with maternal and fetal outcome

Arushi Aggarwal; Mridu Sinha; Tariq Mahmood; Shanti Sah; Gulafshan Anjum

doi:10.21761/jms.v7i02.06

Arushi Aggarwal Junior Resident, Department of Obstetrics & Gynaecology, Department of Biochemistry, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly (U.P.)
Mridu Sinha Professor Department of Obstetrics & Gynaecology, Department of Biochemistry, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly (U.P.)
Tariq Mahmood Professor Department of Obstetrics & Gynaecology, Department of Biochemistry, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly (U.P.)
Shanti Sah Professor Department of Obstetrics & Gynaecology, *Department of Biochemistry, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly (U.P.)
Gulafshan Anjum Assistant Professor, Department of Obstetrics & Gynaecology, Department of Biochemistry, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly (U.P.)

DOI: https://doi.org/10.21761/jms.v7i02.06

Keywords: Fetal, Intrahepatic cholestasis, Maternal, Pregnancy, Serum bile acids.

Abstract

Intrahepatic cholestasis of pregnancy is a
disease characterized by pruritis over limbs associated with
increased level of liver enzymes seen in the second and/
or third trimester after ruling out other causes. Incidence of
intrahepatic cholestasis of pregnancy varies widely, ranging
from < 1 to 27.6%. It causes adverse effects on the maternal
outcome, fetal, and/or neonatal outcome

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