Prognostic Evaluation of Multi-Organ Dysfunction Syndrome in Pediatric Intensive Care Unit: A Crosssectional Study from Western UP

Namrata  Rai; Surabhi  Chandra; Rajeev Kumar  Pandey; Tanveer  Nain; Mayank  Gupta; Anjali  Mishra; Karishma  Aggarwal; Disha  Gupta; Cheerla  Suresh

Namrata Rai Senior Resident, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Surabhi Chandra Professor, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Rajeev Kumar Pandey Junior Resident, Department of General Medicine, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Tanveer Nain Junior Resident, Department of Paediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Mayank Gupta Junior Resident, Department of Paediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Anjali Mishra Junior Resident, Department of Paediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Karishma Aggarwal Junior Resident, Department of Paediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Disha Gupta Junior Resident, Department of Paediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Cheerla Suresh Junior Resident, Department of Paediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.

Keywords: Multi-organ dysfunction syndrome, Pediatric intensive care unit, PELOD score, Sepsis, Prognosis.

Abstract

Introduction: Multi-organ dysfunction syndrome (MODS) significantly contributes to pediatric mortality, especially in low- and middle-income countries. The aim of the study is to evaluate the prognostic utility of the pediatric logistic organ dysfunction (PELOD) score in patients with MODS in Western UP and to study their clinical and laboratory profiles. Material and Methods: A cross-sectional observational study was conducted over 12 months in a tertiary care Pediatric Intensive Care Unit (PICU) in North India, including children aged 1 month to 12 years diagnosed with MODS. Results: Among 94 patients, the majority were male (72.34%) and from rural, lower socioeconomic backgrounds. Sepsis was the leading cause of MODS (95.74%). Higher PELOD scores correlated with increased mortality and longer hospital stays. Conclusion: MODS remains a critical concern in pediatric care. The PELOD score is a valuable tool for prognostication and should be integrated into routine clinical practice.

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