Application of DECAF and BAP-65 to Predict the In-Hospital Mortality of Acute Exacerbation of COPD in SRMSIMS

Abstract

Introduction: Hospitalisation due to acute exacerbations of COPD (AECOPD) is common, and subsequent mortality high. The dyspnoea, eosinopenia, consolidation, acidemia and atrial fibrillation (DECAF) and BAP 65 score was derived for accurate prediction of mortality and risk stratification to inform patient care. We aimed to validate these scores and to compare them in predicting hospital mortality in AECOPD. Material and Methods: 106 patients of AECOPD, admitted during 6 months period were scored at admission using all two scores and their ability to predict in-hospital mortality were analyzed. Results: On receiver-operator characteristic curve analysis, the area under the curve for prediction of in-hospital mortality was 0.791 and 0.885, respectively, for DECAF and BAP-65 scores. Thus, among the two scoring systems, BAP-65 had a maximum area under curve while DECAF had a minimum area under the curve. Sensitivity and specificity values for prediction of in-hospital mortality were 83.3 and 54.3% for DECAF and 83.3 and 84.0% for BAP-65. Thus, BAP-65 was the better predictor with adequate sensitivity and specificity for the in-hospital mortality. Conclusion: BAP-65 was most effective in the prediction of in-hospital mortality.